杨金东，杨金东博士，2009年本科毕业于南开大学，并保送南开大学元素有机国家重点实验室攻读博士，2014年获理学博士学位；2014-2017年于南开大学进行事博士后研究（合作导师：程津培院士）；2017年加入清华大学基础分子科学中心，在有机负氢转移反应的热力学、动力学及反应机理方面取得重要进展和成果，创建了有机化合物键能数据库（iBonD）；2026年4月加入ob电竞官网。以通讯作者在J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nat. Commun., Chem. Soc. Rev., Natl. Sci. Rev., Chem等国际权威期刊上发表成果50余篇，且有多项专利授权。曾获清华大学先进工作者称号（2018年），获中国化学会物理有机化学新人奖（2019年），入选中国科协青年人才托举工程（2019年），入选北京市科协青年人才托举工程（2020年），获国家自然科学基金委青年基金项目（B）资助（2022年）。

研究方向：物理有机化学、主族元素化学、自由基化学等。围绕主族化合物开展结构、性质和催化应用研究，主要包括热力学动力学参数测定，新型主族化合物的设计和制备，主族化合物催化的自由基反应、不对称合成、电催化转化，杂原子手性中心构筑，理论计算等。

杨金东博士目前正组建物理有机化学研究团队。因发展需要，诚邀青年教师2-3名，欢迎有志青年加盟！

主持项目：

1. 基金委面上项目，基于氮杂环磷骨架的碳亲核试剂的开，2026～2029年；

2. 基金委优秀青年项目，化学键能量学研究，2023～2025年；

3. 中石化项目，物质结构-键能/键角数据库研发，2024～2025年；

4. 基金委面上项目，环状氮杂磷氢类化合物氢转移活性及应用研究，2020～2023年；

5. 中国化学会青年人才托举工程项目，2020～2022年；

6. 基金委青年项目，有机化合物化学键能数据库的建立，2017～2019年。

参与项目：

1. 基金委重大项目，基于人工智能辅助的有机小分子催化新反应，2024～2028年；

2. 工信部重大科技公关项目，面向石化行业的基础物性数据库软件项目，2024～2025年；

3. 重点研发计划青年项目，液相物质原子级时空分辨高能电子衍射技术，2022～2026年；

4. 基金委重点项目，化学键能量学数据库建设与拓展，2020～2024年；

5. 科技部基础资源调查专项，化学键能资料整编及数据库的构建，2019～2023年。

代表性成果：

1. Yang, J.-D.; Ji, P.; Xue, X.-S.; Li, X.; Cheng, J.-P., et al. Internet Bond-energy Databank (pK_a and BDE)-iBonD: http://ibond.nankai.edu.cn.

2. Zhang, Y.-S.; Zhong, B.; Dong, L.; Yang, J.-D.*; Cheng, J.-P., Diazaphosphinyl-Radical-Catalyzed Halogen Atom Transfer: Inverting Reactivity Trends for Chloride Activation. Angew. Chem. Int. Ed. 2026, 65, e2642371.

3. Huan, Z.; Han, Z.-C.; Dong, L.; Hu, H.-S.; Yang, J.-D.*; Li, J.; Cheng, J.-P., London Dispersion-Induced Contraction of the Cu─O Bond in Copper(I) Phenolates. Angew. Chem. Int. Ed. 2025, 64, e202513210.

4. Zhang, W.*; Zhu, W.; Yang, J.-D.* Photoexcited Structural Diversification of Carboxylic Acids with Phosphorus Promoter. Angew. Chem. Int. Ed. 2025, 64, e202500657.

5. Xu, K.; Zhang, Y.-S.; Zhong, B.; Zhang, L.*; Yang, J.-D.*; Luo, S.* Organocatalytic Hydrogen Evolution Reaction by Diazaphospholenes. J. Am. Chem. Soc. 2024, 146 25956–25962.

6. Xue, J.; Zhang, Y.-S.; Huan, Z.; Luo, H.-T.; Dong, L.; Yang, J.-D.*; Cheng, J.-P. Phosphonium-Catalyzed Monoreduction of Bisphosphine Dioxides: Origin of Selectivity and Synthetic Applications. J. Am. Chem. Soc. 2024, 146, 9335–9346.

7. Xue, J.; Zhang, Y.-S.; Huan, Z.; Yang, J.-D.*; Cheng, J.-P. Deoxygenation of Phosphine Oxides by P^III/P^V=O Redox Catalysis via Successive Isodesmic Reactions. J. Am. Chem. Soc. 2023, 145, 15589–15599.

8. Wu, J.-Y.; Mo, B.-R.; Yang, J.-D.*; Cheng, J.-P.* A Distinctive Pattern for Substituent Effects on Transition Metal Centers: Enhanced Electron-Donating Capacity of Cationic Palladium Species. CCS Chem. 2023, 5, 1163–1175.

9. Zhang, W.; Luo, H.-T.; Yang, J.-D.* Breakthrough in phosphonylation of alkyl radicals: Alternative access of alkyl phosphonates. Chem 2023, 9, 2735–2737.

10. Zhang, J.; Yang, J.-D.*; Cheng, J.-P.* Chemoselective catalytic hydrodefluorination of trifluoromethylalkenes towards mono-/gem-di-fluoroalkenes under metal-free conditions. Nat. Commun. 2021, 12, 2835.

11. Zhang, J.; Yang, J.-D.*; Cheng, J.-P.* Recent progress in reactivity study and synthetic application of N-heterocyclic phosphorus hydrides. Natl. Sci. Rev. 2021, 8, nwaa253.

12. Wu, J.-Y.; Li, Z.; Yang, J.-D.*; Cheng, J.-P.* Bonding Energetics of Palladium Amido/Aryloxide Complexes in DMSO: Implications for Palladium-Mediated Aniline Activation. Angew. Chem. Int. Ed. 2020, 59, 23782–23790.

13. Zhang, J.; Chen, Q.; Mayer, R. J.; Yang, J.-D.; Ofial, A. R.; Cheng, J.-P.; Mayr, H., Predicting Absolute Rate Constants for Huisgen Reactions of Unsaturated Iminium Ions with Diazoalkanes. Angew. Chem. Int. Ed. 2020, 59, 12527-12533.

14. Yang, Q.; Li, Y.; Yang, J.-D.; Liu, Y.; Zhang, L.; Luo, S.; Cheng, J.-P., Holistic Prediction of the pK_a in Diverse Solvents Based on a Machine-Learning Approach. Angew. Chem. Int. Ed. 2020, 59, 19282-19291.

15. Zhang, J.; Yang, J.-D.*; Cheng, J.-P.* Diazaphosphinyl radical-catalyzed deoxygenation of α-carboxy ketones: a new protocol for chemo-selective C–O bond scission via mechanism regulation. Chem. Sci. 2020, 11, 8476–8481.

16. Zhang, J.; Yang, J.-D.*; Cheng, J.-P.* Diazaphosphinanes as hydride, hydrogen atom, proton or electron donors under transition-metal-free conditions: thermodynamics, kinetics, and synthetic applications. Chem. Sci. 2020, 11, 3672–3679.

17. Zhang, J.; Yang, J.-D.*; Cheng, J.-P.* Exploiting the radical reactivity of diazaphosphinanes in hydrodehalogenations and cascade cyclizations. Chem. Sci. 2020, 11, 4786–4790.

18. Luo, W.; Mao, C.; Ji, P.; Wu, J.-Y.; Yang, J.-D.*; Cheng, J.-P.* Counterintuitive solvation effect of ionic-liquid/DMSO solvents on acidic C–H dissociation and insight into respective solvation. Chem. Sci. 2020, 11, 3365–3370.

19. Zhang, J.; Yang, J.-D.*; Cheng, J.-P.* A Nucleophilicity Scale for the Reactivity of Diazaphospholenium Hydrides: Structural Insights and Synthetic Applications. Angew. Chem. Int. Ed. 2019, z58, 5983–5987.

20. Yang, J.-D.*; Xue, J.; Cheng, J.-P.* Understanding the role of thermodynamics in catalytic imine reductions. Chem. Soc. Rev. 2019, 48, 2913–2926.

21. Zhang, J.^#; Yang, J.-D.^#; Zheng, H.; Xue, X.-S.*; Mayr, H.*; Cheng, J.-P. Exploration of the Synthetic Potential of Electrophilic Trifluoromethylthiolating and Difluoromethylthiolating Reagents. Angew. Chem. Int. Ed. 2018, 57, 12690–12695. (co-first author)

22. Yang, J.-D.^#; Ji, P.^#; Xue, X.-S.; Cheng, J.-P.* Recent Advances and Advisable Applications of Bond Energetics in Organic Chemistry. J. Am. Chem. Soc. 2018, 140, 8611–8623. (co-first author)